miR-515-5p and Notch1 as New Diagnostic Markers of Hepatocellular Carcinoma
Background: Modifications of miRNA expression have been related to various types of cancers including hepatocellular carcinoma (HCC).miRNAs directly act as repressors of gene expression, as they reside in fragile sites, as well as cancer-related genomic regions.Notch signaling is a conserved evolutionary pathway that controls cell functions.The dys